Inactive Ingredients: microcrystalline cellulose, yellow ferric oxide, hydroxypropyl methylcellulose 2910, lactose monohydrate, magnesium stearate, colloidal silicon dioxide, and sodium starch glycolate. FDA pregnancy category C. It is not known whether theophylline will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Get medical help right away if your worsen or if you are using your quick-relief more than usual or more often than prescribed. Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. cheaper version of nizoral nizoral
Phenytoin increases theophylline clearance by increasing microsomal enzyme activity. Theophylline decreases phenytoin absorption. Ishikawa M, Yoneyama Y, Power GG, Araki T "Maternal theophylline administration and breathing movements in late-gestation human fetuses. The information contained in the Truven Health Micromedex products as delivered by Drugs. xalatan
Your pharmacist can provide more information about guaifenesin and theophylline. Do not take more than the recommended dose or use more often than prescribed without checking with your doctor. If your symptoms become worse, contact your doctor. Administer multiple-dose oral activated charcoal and measures to control emesis. Preventing and treating symptoms and blockage of airway due to asthma or other lung diseases such as emphysema or bronchitis. It may also be used for other conditions as determined by your doctor. Some foods may change the effectiveness or increase the side effects of Quibron. Talk to your doctor about how you should take Quibron with regard to food. Do not suddenly change your diet or eating habits without first checking with your doctor.
Decreases theophylline clearance by inhibiting hydroxylation and demethylation. If the serum sample is drawn more than two hours after the dose, the results must be interpreted with caution since the concentration may not be reflective of the peak concentration. In contrast, when signs or symptoms of theophylline toxicity are present, the serum sample should be obtained as soon as possible, analyzed immediately, and the result reported to the clinician without delay. When initiating therapy to guide final dosage adjustment after titration. generic equivalent of precose
Such patients require rapid relief of symptoms and should be treated with an immediate-release or theophylline preparation or other bronchodilators and not with extended-release products. Similarly, a patient with decreased theophylline binding may have a sub-therapeutic total drug concentration while the pharmacologically active unbound concentration is in the therapeutic range. If only total serum theophylline concentration is measured, this may lead to an unnecessary and potentially dangerous dose increase. In patients with reduced protein binding, measurement of unbound serum theophylline concentration provides a more reliable means of dosage adjustment than measurement of total serum theophylline concentration. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs. Horowitz DA, Jablonski W, Mehta KA "Apnea associated with theophylline withdrawal in a term neonate. IV over 30 minutes one time. These observations were not associated with increased mortality. SR has not been adequately studied to determine whether its bioavailability is altered when it is given with food. Gardner MJ, Schatz M, Cousins L, Zeiger R, Middleton E, Jusko WJ "Longitudinal effects of pregnancy on the pharmacokinetics of theophylline. No withdrawal symptoms have been reported following caffeine citrate treatment of less than 3 weeks. The clinical importance of these changes should be weighed against the potential therapeutic benefit of theophylline in individual patients. Quibron-T will not stop an asthma attack once one has started. Be sure to always carry appropriate rescue medicine eg, bronchodilator inhaler with you in case of an asthma attack. Infasurf was administered intratracheally through a side-port adapter into the endotracheal tube. Two attendants, one to instill the Infasurf, the other to monitor the patient and assist in positioning, facilitated the dosing. SR Tablets should not be chewed or crushed.
Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Theophylline blocks adenosine receptors. See package insert for full prescribing information. The pharmacokinetics of theophylline vary widely among similar patients and cannot be predicted by age, sex, body weight or other demographic characteristics. In addition, certain concurrent illnesses and alterations in normal physiology see Table I and co-administration of other drugs see Table II can significantly alter the pharmacokinetic characteristics of theophylline. Within-subject variability in metabolism has also been reported in some studies, especially in acutely ill patients. Contact your doctor or health care provider right away if any of these apply to you. neurontin
Skip next dose and decrease subsequent doses at least 25% even if no adverse effects are present. Recheck serum concentration after 3 days to guide further dosage adjustment. Infasurf calfactant Intratracheal Suspension is supplied sterile in single-use, rubber-stoppered glass vials containing 3 mL NDC 61938-456-03 and 6 mL NDC 61938-456-06 off-white suspension. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Anticipate need for anticonvulsants. Theophylline clearance is decreased by 50% or more in patients with CHF. Theophylline may antagonize non-depolarizing neuromuscular blocking effects; possibly due to phosphodiesterase inhibition. Do not start or stop smoking without first talking to your doctor. Smoking changes the way your body uses theophylline, and you may need to use a different dose. Product Information. Theo-Dur theophylline. 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Following administration of Infasurf, patients should be carefully monitored so that oxygen therapy and ventilatory support can be modified in response to changes in respiratory status. Infasurf therapy is not a substitute for neonatal intensive care. Optimal care of premature infants at risk for RDS and new born infants with RDS who need endotracheal intubation requires an acute care unit organized, staffed, equipped, and experienced with intubation, ventilator management, and general care of these patients. Theophylline increases the force of of diaphragmatic muscles. This action appears to be due to enhancement of uptake through an adenosine-mediated channel. Many drugs can interact with guaifenesin and theophylline. Below is just a partial list.
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Serum theophylline concentration monitoring. Once theophylline enters the systemic circulation, about 40% is bound to plasma protein, primarily albumin. Unbound theophylline distributes throughout body water, but distributes poorly into body fat. Contact your healthcare provider if after taking the oral formulation, symptoms are not relieved within 1 hour or worsen. This list is not complete and many other drugs can interact with theophylline. This includes prescription, over-the-counter, vitamin, and herbal products. Keep a list of all your medicines and show it to any healthcare provider who treats you. online procyclidine remedio
Safety and efficacy of caffeine citrate for treatment of apnea of prematurity have only been established in pediatric patients 28 weeks to less than 33 weeks gestational age. Caffeine and alcohol can increase the side effects of this medication. Avoid drinking large amounts of beverages containing alcohol or caffeine such as coffee, tea, colas eating large amounts of chocolate, or taking nonprescription products that contain caffeine. Store vials in carton until time of use; protect from light. Take the extended-release capsule or tablet every morning at the same time each day. You may take your second dose 10 to 12 hours after the morning dose and before the evening meal, unless your doctor tells you otherwise. If you do not have a dose-measuring device, ask your pharmacist for one. Increases theophylline clearance by induction of microsomal enzyme activity. Infasurf as measured on a pulsating bubble surfactometer. Ex vivo, Infasurf restores the pressure volume mechanics and compliance of surfactant-deficient rat lungs. In vivo, Infasurf improves lung compliance, respiratory gas exchange, and survival in preterm lambs with profound surfactant deficiency. To guide a dose increase, the blood sample should be obtained at the time of the expected peak serum theophylline concentration; 5-6 hours after a dose at steady-state, drawn more than 6 hours after the dose. For most patients, steady-state will be reached after 3 days of dosing when no doses have been missed, no extra doses have been added, and none of the doses have been taken at unequal intervals. Get medical help right away if you have any very serious side effects, including: seizures. Skip next dose and decrease subsequent doses at least 25% even if no adverse effects are present. Recheck serum concentration after 3 days to guide further dosage adjustment. If symptomatic, consider whether overdose treatment is indicated see recommendations for chronic overdosage.
Keep out of the reach of children. Do not stop or change the dose of this medicine without checking first with your doctor. Infasurf was administered through a 5 French feeding catheter inserted into the endotracheal tube. The drugs listed in Table II have the potential to produce clinically significant pharmacodynamic or pharmacokinetic interactions with theophylline. The information in the “Effect ” column of Table II assumes that the interacting drug is being added to a steady-state theophylline regimen. The initial dose was administered within 30 minutes of birth. Repeat doses were administered at 12 and 24 hours if the patient remained intubated. Each dose was administered divided in 2 equal aliquots, and given through a side port adapter into the proximal end of the endotra cheal tube. Each aliquot was given in small bursts over 20-30 inspiratory cycles. After each aliquot was instilled, the infant was positioned with either the right or the left side dependent. Overdose symptoms may include severe forms of some of the side effects listed in this medication guide. Diabetes patients - Quibron-T may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Decreases renal clearance of theophylline. Lithium dose required to achieve a therapeutic serum concentration increased an average of 60%. Ask your health care provider any questions you may have about how to use Quibron-T. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. Increasing the rate of theophylline clearance by extracorporeal methods may rapidly decrease serum concentrations, but the risks of the procedure must be weighed against the potential benefit. Carry an ID card at all times that says you take Quibron. Similar to cimetidine, also increases renal clearance of theophylline. buy now eulexin otc
The dose must be determined by your doctor. However, the total dose is usually not more than 400 milligrams per day, divided and given every 6 to 8 hours. Infasurf is intended for intratracheal use only. Lab tests, including blood theophylline levels, may be performed while you use Quibron-T. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. The initial dose was administered within15 minutes of birth and repeat doses were allowed Greater than or equal to 6 hours following the previous treatment for up to three doses before 96 hours of age if the patient required Greater than or equal to 30% oxygen. The surfactant was given through a 5 French feeding catheter inserted into the endotracheal tube. The drugs listed in Table II have the potential to produce clinically significant pharmacodynamic or pharmacokinetic interactions with theophylline. The information in the “Effect” column of Table II assumes that the interacting drug is being added to a steadystate theophylline regimen. Consult WARNINGS section for additional precautions. Patients with both intraventricular hemorrhage and periventricular leukomalacia.
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Yeh TF, Pildes RS "Transplacental aminophylline toxicity in a neonate. The presence of other medical problems may affect the use of this medicine. How should I take Quibron guaifenesin and theophylline? ikuro.info glimepiride
What happens if I overdose? AND ADMINISTRATION, Table VI. Overview Theophylline is rapidly and completely absorbed after oral administration in solution or immediate-release solid oral dosage form. Theophylline does not undergo any appreciable pre-systemic elimination, distributes freely into fat-free tissues and is extensively metabolized in the liver. Our Uniphyl theophylline, anhydrous Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
There are several readily identifiable causes of reduced theophylline clearance. If the total daily dose is not appropriately reduced in the presence of these risk factors, severe and potentially fatal theophylline toxicity can occur. Store at room temperature away from light and moisture. not store in the bathroom. Keep all away from children and pets. Lowe JC. la récupération de la fibromyalgie par un patient hypothyroïdien résistant à la T4 et de la thyroïde desséchée induite T3. J Myofascial Ther 1 4: 26-31, 1995. Lowe JC. Le traitement métabolique de la fibromyalgie. Boulder, McDowell Publishing Co. 2000. Lowe J, maladie Honeyman-Lowe G. thyroïde et le syndrome de la fibromyalgie. Lyon Mditerrane Mdical: mdecine du Sud-Est 36 1: 15-17, 2000. Derry DM: Conséquences de la TSH. Brit Med J le 29 mai 2000. Skinner GRB, Holmes D, Ahmad A, Davies J, J. Benitez La réponse clinique à la thyroxine sodium chez les patients cliniquement hypothyroïdiens mais biochimiquement euthyroïdiens. J Nutri. Environ Med 10: 115-124, 2000. Greene LW. Informations sur l'hypothyroïdie au site Healthology. how do micardis
Lab tests, including blood theophylline levels, may be performed while you use Quibron. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of theophylline in children. However, children younger than 1 year of age are more likely to have serious side effects, which may require caution and an adjustment in the dose for patients receiving theophylline. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; confusion; dizziness; fast breathing; fast or irregular heartbeat; heart rhythm problems; seizures; severe or persistent nausea, diarrhea, or headache; sleeplessness; tremors; vomiting.